Otospongiosis and sodium fluoride. A clinical double-blind, placebo-controlled study on sodium fluoride treatment in otospongiosis.

Abstract	The effect of sodium fluoride treatment in patients with otospongiosis has been evaluated in a prospective clinical double-blind, placebo-controlled study of 95 patients. The results showed a statistically significant greater deterioration of hearing loss in the placebo group than in the group actively treated with 40 mg of sodium fluoride daily. These results support the view that sodium fluoride can change otospongiotic, active lesions to more dense, inactive otosclerotic lesions.
Authors	P Bretlau, G Salomon, N J Johnsen
Journal	The American journal of otology (Am J Otol) Vol. 10 Issue 1 Pg. 20-2 (Jan 1989) ISSN: 0192-9763 [Print] United States
PMID	2655462 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References	Sodium Fluoride
Topics	Adult Aged Clinical Trials as Topic Double-Blind Method Female Hearing Disorders (drug therapy) Humans Male Middle Aged Otosclerosis (drug therapy) Prospective Studies Sodium Fluoride (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!