A case of methylprednisolone treatment for interstitial pneumonia induced by gefitinibin.

Abstract

In this case, an old man was diagnosed as lung cancer, clinical stage IV. In order to alleviate cancer, this patient was treated with gefitinib. Three months later, symptoms such as a significant weakness, chest tightness and shortness of breath after sports arised and intensifying. Implosive therapy with high dose methylprednisolone is used to control the weakness caused by gefitinib. Eight days after treatment, patient's condition significantly improved. The use of methylprednisolone can effectively treat interstitial pneumonia induced by gefitinibin, help patients get better from critical condition such as type I respiratory failure. This new discovery is a good guidance for clinical treatment of gefitinibin caused interstitial pneumonia.

• Authors: Jun Yan, Chun Wang, Qinfang Zhang, Xiaoou Chen, Weiwei Yu
• Journal: International journal of clinical and experimental medicine (Int J Clin Exp Med) Vol. 8 Issue 8 Pg. 14150-3 ( 2015) ISSN: 1940-5901 [Print] United States
• PMID: 26550386 (Publication Type: Case Reports)