Abstract | OBJECTIVE: The purpose of this study was to determine the efficacy of the Lidopat(®) 5% skin patch in relieving rib fracture pain. SUBJECTS AND METHODS: From June 2009 to May 2011, 44 trauma patients with isolated rib fractures were enrolled in this study and randomized in a double-blind method into 2 groups. The experimental group (group E: 27 patients) used a Lidopat(®) 5% skin patch at the trauma site and took an oral analgesic drug for pain relief. The placebo group (group P: 17 patients) used a placebo vehicle patch and an oral analgesic drug. RESULTS: The mean age, weight and hospital stay of patients were 56.8 ± 13.8 years, 67.4 ± 12.6 kg and 6.34 ± 1.3 days, respectively. In the first 4 days, there were no significant differences in pain scores between the groups (p > 0.05). After the 5th day, the average pain score was significantly less in group E (mean 1.5) than in group P (mean 3.10; p < 0.05). There was no significant difference in the number of fractured ribs between groups (p = 0.904). The use of meperidine and the length of hospital stay (6.0 vs. 6.9 days) were both significantly less in group E (p = 0.043 and 0.009, respectively). CONCLUSION: In this study, the use of the Lidopat(®) 5% skin patch in patients with isolated rib fractures alleviated pain and shortened the hospital stay, and a lower dose of pain-relieving medication was used.
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Authors | Yu-Jen Cheng |
Journal | Medical principles and practice : international journal of the Kuwait University, Health Science Centre
(Med Princ Pract)
Vol. 25
Issue 1
Pg. 36-9
( 2016)
ISSN: 1423-0151 [Electronic] Switzerland |
PMID | 26539836
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | © 2015 S. Karger AG, Basel. |
Chemical References |
- Analgesics, Opioid
- Anesthetics, Local
- Lidocaine
- Meperidine
|
Topics |
- Analgesics, Opioid
(therapeutic use)
- Anesthetics, Local
(administration & dosage)
- Double-Blind Method
- Drug Utilization
(statistics & numerical data)
- Female
- Humans
- Length of Stay
(statistics & numerical data)
- Lidocaine
(administration & dosage)
- Male
- Meperidine
(therapeutic use)
- Middle Aged
- Pain
(drug therapy, etiology)
- Prospective Studies
- Rib Fractures
(complications)
- Transdermal Patch
- Visual Analog Scale
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