Acquired multiple acyl-CoA dehydrogenase deficiency and marked selenium deficiency causing severe rhabdomyolysis in a horse.

Abstract

This report describes a case of severe rhabdomyolysis in a pregnant mare associated with histopathologic and biochemical features of both selenium deficiency and acquired multiple acyl-CoA dehydrogenase deficiency (MADD) due to seasonal pasture myopathy (SPM). This case highlights the importance of assessing plasma selenium levels in horses with clinical signs of pasture myopathy as this deficiency may be a contributing or exacerbating factor.

• Authors: Diego E Gomez, Stephanie J Valberg, K Gary Magdesian, Paul E Hanna, Jeanne Lofstedt
• Journal: The Canadian veterinary journal = La revue veterinaire canadienne (Can Vet J) Vol. 56 Issue 11 Pg. 1166-71 (Nov 2015) ISSN: 0008-5286 [Print] Canada
• PMID: 26538673 (Publication Type: Case Reports, Journal Article)

Chemical References

• Selenium

Topics

• Animals
• Female
• Horse Diseases (etiology, pathology)
• Horses
• Malnutrition (complications, veterinary)
• Multiple Acyl Coenzyme A Dehydrogenase Deficiency (blood, veterinary)
• Muscle, Skeletal (enzymology)
• Muscular Diseases (complications, etiology, pathology, veterinary)
• Pregnancy
• Pregnancy Complications
• Rhabdomyolysis (etiology, veterinary)
• Seasons
• Selenium (deficiency)