Abstract | BACKGROUND: METHODS:
Oxaliplatin (4 mg/kg) was administered intravenously twice per week for 4 weeks, and mechanical allodynia was evaluated using the von Frey test in rats. Axonal degeneration was assessed by toluidine blue staining of sciatic nerves. RESULTS: CONCLUSION:
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Authors | Shunsuke Fujita, Soichiro Ushio, Nana Ozawa, Ken Masuguchi, Takehiro Kawashiri, Ryozo Oishi, Nobuaki Egashira |
Journal | PloS one
(PLoS One)
Vol. 10
Issue 11
Pg. e0141921
( 2015)
ISSN: 1932-6203 [Electronic] United States |
PMID | 26536615
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Hypoglycemic Agents
- Organoplatinum Compounds
- Peptides
- Venoms
- Oxaliplatin
- Exenatide
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Topics |
- Adenocarcinoma
(drug therapy, pathology)
- Animals
- Antineoplastic Agents
(toxicity)
- Cell Survival
(drug effects)
- Colonic Neoplasms
(drug therapy, pathology)
- Exenatide
- Hyperalgesia
(chemically induced, drug therapy, pathology)
- Hypoglycemic Agents
(pharmacology)
- Male
- Mice
- Mice, Inbred BALB C
- Neurites
(drug effects)
- Organoplatinum Compounds
(toxicity)
- Oxaliplatin
- PC12 Cells
- Peptides
(pharmacology)
- Peripheral Nervous System Diseases
(chemically induced, drug therapy, pathology)
- Rats
- Rats, Sprague-Dawley
- Sciatic Nerve
(cytology, drug effects)
- Venoms
(pharmacology)
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