A participatory epidemiological (PE) study was conducted with livestock keepers in Moroto and Kotido districts, Karamoja Region, Uganda, between October and December 2013 to determine the management options and relative importance of
tick-borne diseases (
TBDs) amongst transhumant zebu cattle. Data collection involved 24 focus group discussions (each comprising 8-12 people) in 24 settlement areas (manyattas), key informant interviews (30), direct observation, a review of surveillance data, clinical examination, and laboratory confirmation of cases of
TBDs. Methods used in group discussions included semi-structured interviews, simple ranking, pairwise ranking, matrix scoring, proportional piling and participatory mapping. The results of pairwise comparison showed the Ngakarimojong-named diseases, lokit (
East Coast fever, ECF),
lopid (
anaplasmosis), loukoi (contagious bovine
pleuropneumonia, CBPP), lokou (heartwater) and lokulam (
babesiosis), were considered the most important
cattle diseases in Moroto in that order, while ECF,
anaplasmosis, trypanosomosis (ediit), CBPP and nonspecific diarrhoea (loleo) were most important in Kotido. Strong agreement between informant groups (Kendall's coefficient of concordance W=0.568 and 0.682; p<0.001) in pairwise ranking indicated that the diseases were a common problem in selected districts.
East Coast fever had the highest median score for incidence (18% [range: 2, 33]) in Moroto, followed by
anaplasmosis (17.5% [8,32]) and CBPP (9% [1,21]). Most animals that suffered from ECF,
anaplasmosis, heartwater and
babesiosis died, as the respective median scores for case fatality rates (CFR) were 89.5% (42, 100), 82.8% (63, 100), 66.7% (20, 100) and 85.7% (0, 100). In Kotido, diseases with high incidence scores were ECF (21% [6,32]),
anaplasmosis (17% [10,33]) and trypanosomosis (8% [2,18]). The CFRs for ECF and
anaplasmosis were 81.7% (44, 100) and 70.7% (48, 100), respectively. Matrix scoring revealed that disease indicators showed strong agreement (W=0.382-0.659, p<0.05-p<0.001) between informant groups. Inadequate knowledge, poor veterinary services and limited availability of drugs were the main constraints that hindered the control of
TBDs. Hand picking of ticks was done by all pastoralists while hand spraying with
acaricides was irregular, often determined by availability of
drug supplies and money. It was concluded that
TBDs, particularly ECF and
anaplasmosis were important diseases in this pastoral region. Results from this study may assist in the design of feasible control strategies.