[Beta 2-microglobulin and a test using 169 Yb-DTPA in evaluating glomerular filtration and reabsorption of protein in gynecologic cancer patients].

Abstract

Radionuclide investigation (a test with 169Yb-DTPA) and radioimmunoassay determination of the concentration of beta 2-MG in the blood serum and urine were performed to study glomerular filtration and protein reabsorption in patients with myoma (57) and uterine body cancer (51) before operation, on the 1st, 3rd, 5th and 14th days of the postoperative period, and 6-12 mos. after operation. At the same time 24 healthy women (controls) were investigated. The greatest changes of glomerular filtration and protein reabsorption in the patients of the study group were shown to develop on the 5th day after operation. There was parallelism of the results of radionuclide investigation and the radioimmunoassay with beta 2-MG therefore the latter can be recommended for the diagnosis of renal dysfunction in the early postoperative period.

• Authors: O P Modnikov
• Journal: Meditsinskaia radiologiia (Med Radiol (Mosk)) Vol. 34 Issue 4 Pg. 57-9 (Apr 1989) ISSN: 0025-8334 [Print] Russia (Federation)
• Vernacular Title: Beta 2-microglobulin i proba s 169Yb-DTPK v otsenke klubochkovoĭ filtratsii i reabsorbtsii belka u onkoginekologicheskikh bol'nykh.
• PMID: 2651842 (Publication Type: Journal Article)

Chemical References

• Radioisotopes
• beta 2-Microglobulin
• Pentetic Acid
• Ytterbium

Topics

• Female
• Humans
• Kidney Glomerulus (diagnostic imaging, physiopathology)
• Leiomyoma (diagnostic imaging, physiopathology, surgery)
• Pentetic Acid
• Radioimmunoassay
• Radioisotope Renography
• Radioisotopes
• Uterine Neoplasms (diagnostic imaging, physiopathology, surgery)
• Ytterbium
• beta 2-Microglobulin (analysis, urine)