Type 1 reaction masquerading clinically as ENL: A Case Report.

Abstract

Attention is drawn to a Type 1 reaction masquerading clinically as ENL. Histology showed no evidence of ENL but suggested heightened T-cell activity (CMI), a characteristic feature of Type 1 reaction. We present a case of a 29 year old man diagnosed as lepromatous leprosy with recurrent Type 2 reaction treated with thalidomide for 2 years. The patient was referred to our institute from a teaching hospital. Skin biopsies were carried out during two separate eruptive episodes 2 months apart. Histopathology showed heightened T-cell activity, but no evidence of ENL.

• Authors: Ashish Khodke, Vanaja P Shetty
• Journal: Leprosy review (Lepr Rev) Vol. 86 Issue 2 Pg. 202-5 (Jun 2015) ISSN: 0305-7518 [Print] England
• PMID: 26502694 (Publication Type: Case Reports, Journal Article)

Chemical References

• Leprostatic Agents
• Thalidomide

Topics

• Adult
• Erythema Nodosum (diagnosis)
• Humans
• Leprostatic Agents (therapeutic use)
• Leprosy, Lepromatous (diagnosis, drug therapy, pathology)
• Male
• Thalidomide (therapeutic use)