Plummer-Vinson Syndrome in Children.

Plummer-Vinson syndrome (PVS), also called Kelly-Paterson syndrome, is a rare cause of dysphagia in children. This syndrome associates single or multiple webs in the upper esophagus with frequent iron deficiency.
We reported 3 pediatric cases of PVS before analyzing all of the cases of PVS in children reported in the PubMed and EMBASE databases.
Among 17 reported PVS cases in children, all of the patients experienced iron-deficiency anemia, and no immunological disease was reported. The male/female ratio was 1/1.9, and most cases were observed in adolescents. Conversely to adults, endoscopic dilation was often necessary because dysphagia resisted iron supplementation. A single dilation was usually sufficient. One case of pediatric PVS experienced esophageal cancer in adulthood.
In the case of dysphagia in children, a swallow barium exploration with lateral incidence should look for PVS. Conversely to adults, an endoscopic dilation is frequently necessary to control dysphagia in children.
AuthorsMathilde Butori, Sana Mahmoudi, Emmanuelle Dugelay-Ecochard, Nadia Belarbi, Marc Bellaïche, Jean-Pierre Hugot, Jérôme Viala
JournalJournal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr) Vol. 61 Issue 5 Pg. 547-52 (Nov 2015) ISSN: 1536-4801 [Electronic] United States
PMID26502163 (Publication Type: Journal Article)

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