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Plummer-Vinson Syndrome in Children.

AbstractOBJECTIVES:
Plummer-Vinson syndrome (PVS), also called Kelly-Paterson syndrome, is a rare cause of dysphagia in children. This syndrome associates single or multiple webs in the upper esophagus with frequent iron deficiency.
METHODS:
We reported 3 pediatric cases of PVS before analyzing all of the cases of PVS in children reported in the PubMed and EMBASE databases.
RESULTS:
Among 17 reported PVS cases in children, all of the patients experienced iron-deficiency anemia, and no immunological disease was reported. The male/female ratio was 1/1.9, and most cases were observed in adolescents. Conversely to adults, endoscopic dilation was often necessary because dysphagia resisted iron supplementation. A single dilation was usually sufficient. One case of pediatric PVS experienced esophageal cancer in adulthood.
CONCLUSIONS:
In the case of dysphagia in children, a swallow barium exploration with lateral incidence should look for PVS. Conversely to adults, an endoscopic dilation is frequently necessary to control dysphagia in children.
AuthorsMathilde Butori, Sana Mahmoudi, Emmanuelle Dugelay-Ecochard, Nadia Belarbi, Marc Bellaïche, Jean-Pierre Hugot, Jérôme Viala
JournalJournal of pediatric gastroenterology and nutrition (J Pediatr Gastroenterol Nutr) Vol. 61 Issue 5 Pg. 547-52 (Nov 2015) ISSN: 1536-4801 [Electronic] United States
PMID26502163 (Publication Type: Journal Article)

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