Abstract | OBJECTIVES: METHODS: The present study included 57 patients with erectile dysfunction who satisfied all the following conditions: more than 6-months history of erectile dysfunction, sexual health inventory for men score of ≤ 12 without phosphodiesterase type-5 inhibitor, erection hardness score grade 1 or 2, mean penile circumferential change by erectometer assessing sleep related erection of < 25 mm and non-neurological pathology. Patients were treated by a low-energy shock waves generator (ED1000; Medispec, Gaithersburg, MD, USA). A total of 12 shock wave treatments were applied. Sexual health inventory for men score, erection hardness score with or without phosphodiesterase type-5 inhibitor, and mean penile circumferential change were assessed at baseline, 1, 3 and 6 months after the termination of low-intensity shock wave therapy. RESULTS: Of 57 patients who were assigned for the low-intensity shock wave therapy trial, 56 patients were analyzed. Patients had a median age of 64 years. The sexual health inventory for men and erection hardness score (with and without phosphodiesterase type-5 inhibitor) were significantly increased (P < 0.001) at each time-point. The mean penile circumferential change was also increased from 13.1 to 20.2 mm after low-intensity shock wave therapy (P < 0.001). In the multivariate analysis, age and the number of concomitant comorbidities were statistically significant predictors for the efficacy. CONCLUSIONS:
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Authors | Shin-ichi Hisasue, Toshiyuki China, Akira Horiuchi, Masaki Kimura, Keisuke Saito, Shuji Isotani, Hisamitsu Ide, Satoru Muto, Raizo Yamaguchi, Shigeo Horie |
Journal | International journal of urology : official journal of the Japanese Urological Association
(Int J Urol)
Vol. 23
Issue 1
Pg. 80-4
(Jan 2016)
ISSN: 1442-2042 [Electronic] Australia |
PMID | 26501992
(Publication Type: Clinical Trial, Journal Article)
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Copyright | © 2015 The Japanese Urological Association. |
Chemical References |
- Phosphodiesterase 5 Inhibitors
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Topics |
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Aging
(physiology)
- Diabetes Complications
(complications)
- Dyslipidemias
(complications)
- Erectile Dysfunction
(complications, physiopathology, therapy)
- Humans
- Hypertension
(complications)
- Male
- Middle Aged
- Myocardial Ischemia
(complications)
- Penile Erection
(physiology)
- Phosphodiesterase 5 Inhibitors
(therapeutic use)
- Prospective Studies
- Severity of Illness Index
- Surveys and Questionnaires
- Treatment Outcome
- Ultrasonic Therapy
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