Abstract | BACKGROUND: CASE PRESENTATION: A 24-year-old man with bipolar disorder was treated with aripiprazole and gradually developed tardive dystonia. Thorough medical and neurological examinations were performed to rule out other possible causes of tardive dystonia. Clozapine was administered when the patient did not improve following long-term withdrawal of aripiprazole or adjuvant medications. Before administration of clozapine, the patient was experiencing severe dystonia as assessed by the Extrapyramidal Symptom Rating Scale. Dystonic symptoms began to improve about 1 month after starting administration of clozapine and were completely resolved 3 months after clozapine administration. CONCLUSIONS:
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Authors | Soohyun Joe, Jangho Park, Jongseok Lim, Choongman Park, Joonho Ahn |
Journal | BMC psychiatry
(BMC Psychiatry)
Vol. 15
Pg. 253
(Oct 19 2015)
ISSN: 1471-244X [Electronic] England |
PMID | 26482558
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antipsychotic Agents
- Aripiprazole
- Clozapine
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Topics |
- Antipsychotic Agents
(adverse effects, therapeutic use)
- Aripiprazole
(adverse effects)
- Bipolar Disorder
(drug therapy)
- Clozapine
(therapeutic use)
- Dyskinesia, Drug-Induced
(drug therapy, etiology)
- Humans
- Male
- Movement Disorders
(drug therapy, etiology)
- Neurologic Examination
- Psychotic Disorders
(drug therapy)
- Treatment Outcome
- Young Adult
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