Abstract | STUDY OBJECTIVE: To assess the utility of TachoSil for achieving hemostasis after loop electrosurgical excision procedure (LEEP). DESIGN: Case-control study (Canadian Task Force Classification II-2). SETTING: University hospital. PATIENTS: One hundred seventy-three patients who underwent LEEP. INTERVENTIONS: Patients were managed by LEEP with application of TachoSil ( TachoSil group, n=75) or without application of TachoSil (control group, n=94). MEASUREMENTS AND MAIN RESULTS: Patient characteristics (age, specimen depth, resection margin, LEEP histopathology, or use of TachoSil) except for parity were similar between the two study groups. Severe bleeding requiring any intervention developed in 14% of patients (24 of 169 patients), without any statistically significant difference between the two groups (11% in the TachoSil group vs. 17% in the control group; P=0.274). On the logistic regression analysis, other potential clinico-pathologic parameters, including age, parity, specimen depth, involvement of the resection margin, and LEEP histopathology, were not correlated with severe bleeding after LEEP. CONCLUSION:
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Authors | Jeong Jin Kim, Woo Young Kim, Doo Haeng Lee, Jun Hyeok Kang, Taejong Song, Kyo Won Lee, Kye Hyun Kim |
Journal | European journal of obstetrics, gynecology, and reproductive biology
(Eur J Obstet Gynecol Reprod Biol)
Vol. 194
Pg. 245-8
(Nov 2015)
ISSN: 1872-7654 [Electronic] Ireland |
PMID | 26476696
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2015 Elsevier Ireland Ltd. All rights reserved. |
Chemical References |
- Drug Combinations
- TachoSil
- Fibrinogen
- Thrombin
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Topics |
- Adult
- Case-Control Studies
- Drug Combinations
- Electrosurgery
(adverse effects)
- Female
- Fibrinogen
(therapeutic use)
- Hemostasis, Surgical
(methods)
- Humans
- Middle Aged
- Postoperative Hemorrhage
(prevention & control)
- Retrospective Studies
- Surgical Sponges
- Thrombin
(therapeutic use)
- Uterine Cervical Neoplasms
(pathology, surgery)
- Uterine Cervical Dysplasia
(pathology, surgery)
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