Abstract |
We report a case of skin necrosis of the nasal tip after an injection of ribose cross-linked porcine atelocollagen ( Evolence; Colbar Life Science Ltd, Herzliya, Israel). A 22-year-old woman had a nasal augmentation. From the glabella to the nasal tip, 10 strokes were injected using 0.6 mL of Evolence. On the day of the injection, her nasal tip became cyanotic; a day after it, an erythematous condition developed and a white cheeselike material appeared. On the second day, it became necrotic. Epithelialization was completed for 2 weeks. Despite laser therapy, permanent scarring of the nasal tip was prominent at the 18-month follow-up. It was thought that the skin necrosis is caused by vascular interruption rather than by hypersensitivity because the skin necrosis was confined to the nasal tip. To avoid vascular interruption from a filler injection, aspiration is needed before injection. The least amount of filler should be released in each stroke with low-pressure injection.
|
Authors | Seong Kee Kim, Joo Ho Kim, Kun Hwang |
Journal | The Journal of craniofacial surgery
(J Craniofac Surg)
Vol. 26
Issue 7
Pg. 2211-2
(Oct 2015)
ISSN: 1536-3732 [Electronic] United States |
PMID | 26468812
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Cross-Linking Reagents
- Dermal Fillers
- dermicol-P35 27G
- Ribose
- Collagen
|
Topics |
- Cicatrix
(etiology, surgery)
- Collagen
(adverse effects, chemistry)
- Cosmetic Techniques
(adverse effects)
- Cross-Linking Reagents
(chemistry)
- Cyanosis
(etiology)
- Dermal Fillers
(adverse effects, chemistry)
- Erythema
(etiology)
- Female
- Follow-Up Studies
- Humans
- Injections
(adverse effects)
- Laser Therapy
- Necrosis
- Nose
(pathology)
- Re-Epithelialization
(physiology)
- Ribose
(chemistry)
- Skin
(pathology)
- Young Adult
|