Abstract | OBJECTIVE: This study aimed to evaluate the relationship between forkhead box P3 (Foxp3) expression and clinicopathological characteristics of cervical cancer and to explore the influence of Foxp3 on the biological behaviors of cervical cancer cells. METHODS: In this study, immunohistochemistry, lentivirus mediated transfection, Transwell assay; CCK-8 assay, real-time PCR and flow cytometry were employed to confirm the roles of Foxp3 in the occurrence and development of cervical cancer. RESULTS: CONCLUSION:
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Authors | Qingshuang Luo, Shulan Zhang, Heng Wei, Xiaoao Pang, Huijie Zhang |
Journal | International journal of clinical and experimental pathology
(Int J Clin Exp Pathol)
Vol. 8
Issue 8
Pg. 8717-30
( 2015)
ISSN: 1936-2625 [Electronic] United States |
PMID | 26464616
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- FOXP3 protein, human
- Forkhead Transcription Factors
- RNA, Small Interfering
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Topics |
- Adenocarcinoma
(pathology)
- Adult
- Aged
- Blotting, Western
- Carcinoma, Squamous Cell
(pathology)
- Female
- Flow Cytometry
- Forkhead Transcription Factors
(biosynthesis)
- Humans
- Immunohistochemistry
- Middle Aged
- RNA, Small Interfering
- Real-Time Polymerase Chain Reaction
- Transfection
- Uterine Cervical Neoplasms
(pathology)
- Uterine Cervical Dysplasia
(pathology)
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