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Do local analgesics injected at the time of third molar removal under general anaesthesia reduce significantly post operative analgesic requirements? A double-blind controlled trial.

Abstract
A prospective, controlled, randomised, double-blind trial suggested that: 1. The use of bupivacaine 0.5% plain and prilocaine 3% with felypressin 0.03 i.u./ml. as peroperative local analgesics reduce postoperative pain scores recorded on the first postoperative morning (P less than 0.05). 2. Bupivacaine 0.5% plain reduces postoperative opiate requirements (P less than 0.025). 3. Patients do not find peroperative bilateral inferior alveolar and lingual nerve blocks with buccal infiltrations significantly unpleasant. Thus peri-operative bupivacaine 0.5% is a valuable adjunct to third molar removal under general anaesthesia.
AuthorsJ R Tuffin, D R Cunliffe, S R Shaw
JournalThe British journal of oral & maxillofacial surgery (Br J Oral Maxillofac Surg) Vol. 27 Issue 1 Pg. 27-32 (Feb 1989) ISSN: 0266-4356 [Print] Scotland
PMID2645933 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Analgesics
  • Prilocaine
  • Bupivacaine
Topics
  • Adolescent
  • Adult
  • Analgesics (administration & dosage)
  • Anesthesia, Dental
  • Anesthesia, General
  • Bupivacaine (administration & dosage)
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Humans
  • Intraoperative Care
  • Male
  • Molar, Third (surgery)
  • Pain, Postoperative (prevention & control)
  • Prilocaine (administration & dosage)
  • Prospective Studies
  • Random Allocation
  • Tooth Extraction

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