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Prothrombin Complex Concentrate for Intracerebral Hemorrhage Secondary to Vitamin K Deficiency Bleeding in a 6-Week-Old Child.

Abstract
Four-factor prothrombin complex concentrate is approved for use of life-threatening bleeding secondary to vitamin K antagonism in adults. We describe the use of four-factor prothrombin complex concentrate for hemostasis in a 6-week-old child with life-threatening vitamin K dependent-bleeding who never received vitamin K prophylaxis at birth.
AuthorsMegan A Rech, Lindsay Wittekindt, Samantha D Friedman, Kendall Kling, David Ubogy
JournalThe Journal of pediatrics (J Pediatr) Vol. 167 Issue 6 Pg. 1443-4 (Dec 2015) ISSN: 1097-6833 [Electronic] United States
PMID26454577 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2015 Elsevier Inc. All rights reserved.
Chemical References
  • Blood Coagulation Factors
  • prothrombin complex concentrates
Topics
  • Blood Coagulation (drug effects)
  • Blood Coagulation Factors (administration & dosage)
  • Cerebral Hemorrhage (diagnosis, drug therapy, etiology)
  • Female
  • Humans
  • Infant, Newborn
  • Injections, Intravenous
  • Vitamin K Deficiency Bleeding (blood, complications, drug therapy)

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