ST Segment Elevation ECG Changes During Pharmacologic Stress With Regadenoson.

Abstract

Regadenoson is a pharmacologic stress agent that has been widely adopted as an alternative over other pharmacologic vasodilator agents due to its ease of use, patient tolerance, and safety profile. We report the case of dynamic ST-segment elevation electrocardiogram changes after regadenoson injection during an inpatient single-photon emission computed tomography myocardial perfusion stress test, with subsequent coronary angiography revealing the presence of hemodynamically significant coronary artery disease. Our findings confirm that transient regadenoson-induced ST-segment elevations are a marker for hemodynamically significant disease even in the setting of low-risk SPECT perfusion images.

• Authors: Salima Qamruddin, Henry W Huang, Anil Mehra, Shahram Bonyadlou, Andrew J Yoon
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 41 Issue 1 Pg. 62-4 (Jan 2016) ISSN: 1536-0229 [Electronic] United States
• PMID: 26447370 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adenosine A2 Receptor Agonists
• Purines
• Pyrazoles
• regadenoson

Topics

• Adenosine A2 Receptor Agonists (adverse effects)
• Coronary Angiography
• Coronary Artery Disease (diagnostic imaging)
• Electrocardiography
• Exercise Test
• Heart Rate (drug effects)
• Humans
• Male
• Middle Aged
• Myocardial Perfusion Imaging
• Purines (adverse effects)
• Pyrazoles (adverse effects)
• Tomography, Emission-Computed, Single-Photon