Abstract | PURPOSE: METHODS: Between January 2000 and December 2011, we performed 195 DD renal transplants. After the exclusion of primary nonfunctional grafts (n = 4), the study recipients were divided into two groups-group I, DGF (n = 31, 16.2%); group II, non-DGF (n = 160, 83.8%). The following variables were compared: donor and recipient characteristics, patient and graft survival, postoperative renal function, acute rejection (AR) episodes, and the rates of surgical and infectious complications. RESULTS: Donor-related variables that showed significant differences included hypertension (P = 0.042), diabetes (P = 0.025), and prerecovery serum creatinine levels (P < 0.001). However, there were no significant differences in recipient-related factors. One significantly different transplant-related factor was positive panel reactive antibody (PRA > 20%, P = 0.008). On multivariate analysis, only the prerecovery serum creatinine level (P < 0.001; hazard ratio [HR], 1.814) was an independent risk factor for the development of DGF. A Cox multivariate analysis of risk factors for graft survival identified these independent risk factors for graft survival: nephron mass (donor kidney weight to recipient body weight ratio) index (P = 0.026; HR, 2.328), CMV infection (P = 0.038; HR, 0.114), and AR episode (P = 0.038; HR, 0.166). CONCLUSION: In DD KT, an independent risk factor for DGF was the prerecovery serum creatinine level. Although there was a significant difference in graft survival between the DGF and non-DGF groups, DGF was not an independent risk factor for graft failure in this study.
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Authors | Chang Ho Seo, Jeong Il Ju, Mi-Hyeong Kim, Kang Woong Jun, Sang-Hyun Ahn, Jeong Kye Hwang, Sang Dong Kim, Sun Cheol Park, Bum Soon Choi, Ji Il Kim, Chul Woo Yang, Yong Soo Kim, In Sung Moon |
Journal | Annals of surgical treatment and research
(Ann Surg Treat Res)
Vol. 89
Issue 4
Pg. 208-14
(Oct 2015)
ISSN: 2288-6575 [Print] Korea (South) |
PMID | 26446498
(Publication Type: Journal Article)
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