Optimal Vitamin D Supplementation Levels for Cardiovascular Disease Protection.

Abstract

First described in relation to musculoskeletal disease, there is accumulating data to suggest that vitamin D may play an important role in cardiovascular disease (CVD). In this review we aim to provide an overview of the role of vitamin D status as both a marker of and potentially causative agent of hypertension, coronary artery disease, heart failure, atrial fibrillation, stroke, and peripheral vascular disease. The role of vitamin D levels as a disease marker for all-cause mortality is also discussed. We review the current knowledge gathered from experimental studies, observational studies, randomised controlled trials, and subsequent systematic reviews in order to suggest the optimal vitamin D level for CVD protection.

• Authors: Sebastian T Lugg, Phillip A Howells, David R Thickett
• Journal: Disease markers (Dis Markers) Vol. 2015 Pg. 864370 ( 2015) ISSN: 1875-8630 [Electronic] United States
• PMID: 26435569 (Publication Type: Journal Article, Review)

Chemical References

• Vitamins
• Vitamin D

Topics

• Animals
• Cardiovascular Diseases (drug therapy, epidemiology, prevention & control)
• Humans
• Vitamin D (administration & dosage, therapeutic use)
• Vitamin D Deficiency (drug therapy, epidemiology)
• Vitamins (administration & dosage, therapeutic use)