[Thyroid hormones and thyrotropin in the population of patients with endemic goiter in the Kolno community].

Abstract

The studies comparing the actions of dried thyroid gland (Thyroideum-Polfa) with L-thyroxine sodium (L-T4) were carried out in 20 female patients with hypothyroidism, including 19 patients with the primary hypothyroidism and 1 patient with hypothyroidism secondary to pituitary deficiency. Administration of the dried thyroid gland did not normalize blood serum T4 an TSH in any patient. Normal serum T4 or even slightly increased was achieved in all patients treated with L-T4. Serum TSH was normalized in 17 patients with the primary hypothyroidism. The following conclusions have been drawn: 1. Dried thyroid gland (Thyroideum-Polfa) is ineffective in the treatment of hypothyroidism. 2. Serum TSH remains elevated despite normal serum T3 in cases of the primary hypothyroidism with decreased serum T4 levels. 3. Sodium salt of L-thyroxine should be used for the treatment of hypothyroidism. 1-Triiodothyronine sodium may be used as an adjuvant therapy.

• Authors: A Grabowska, A Zonenberg, W Zarzycki, A Sredzińska, I Kinalska
• Journal: Polski tygodnik lekarski (Warsaw, Poland : 1960) (Pol Tyg Lek) 1989 Aug 7-14 Vol. 44 Issue 32-33 Pg. 761-3 ISSN: 0032-3756 [Print] Poland
• Vernacular Title: Hormony tarczycy oraz tyreotropina w populacji osób z wolem endemicznym na terenie gminy Kolno.
• PMID: 2641803 (Publication Type: English Abstract, Journal Article)

Chemical References

• Triiodothyronine
• Triiodothyronine, Reverse
• Thyrotropin
• Thyroxine

Topics

• Adolescent
• Adult
• Aged
• Child
• Female
• Goiter, Endemic (blood, diagnosis, epidemiology)
• Humans
• Male
• Middle Aged
• Poland
• Thyrotropin (blood)
• Thyroxine (blood)
• Triiodothyronine (blood)
• Triiodothyronine, Reverse (blood)