Treatment of vaginal candidiasis with ketoconazole, a new, orally active, antimycotic.

Abstract

The efficacy of a new, orally active antimycotic, ketoconazole, in the treatment of vaginal candidiasis was studied at different doses involving 63 patients. All patients had subjective complaints and were mycologically positive. There was no significant difference in the cure rates of the different doses. The oral treatment was successful in 55 out of 63 patients (87.3%). No correlation was found between the relapse rate of vaginal candidiasis and the dose regimen. There were no serious side-effects, and no significant changes were reported in hematological and biochemical parameters.

• Authors: M P Bisschop, J M Merkus, H Scheygrond, J Van Cutsem, A van de Kuy
• Journal: European journal of obstetrics, gynecology, and reproductive biology (Eur J Obstet Gynecol Reprod Biol) Vol. 9 Issue 4 Pg. 253-9 (Aug 1979) ISSN: 0301-2115 [Print] Ireland
• PMID: 264094 (Publication Type: Journal Article)

Chemical References

• Ketoconazole

Topics

• Administration, Oral
• Adult
• Candidiasis, Vulvovaginal (drug therapy)
• Dose-Response Relationship, Drug
• Female
• Humans
• Ketoconazole (therapeutic use)
• Middle Aged
• Pilot Projects