[Monitoring of 4 patients with heparin-induced thrombocytopenia after complex congenital heart surgery].

Abstract

From July 2013 to February 2015, 4 infant patients with complex congenital heart disease, who underwent open heart surgery in Xiangya Hospital of Central South University, were diagnosed as heparin-induced thrombocytopenia (HIT). After comprehensive treatments, such as intensive monitoring of the platelet count, close observation of thromboembolic skin lesions and close monitoring of argatroban therapy, 3 patients were cured and 1 died. HIT is rare but serious in patients who received heparin therapy. The incidence of mortality and thrombosis is very high. Early identification and diagnosis of high-risk groups can improve the prognosis.

• Authors: Jianhui Zhou, Jing Peng, Qian Li, Sisi Wei, Wenya Wu
• Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences (Zhong Nan Da Xue Xue Bao Yi Xue Ban) Vol. 40 Issue 9 Pg. 1039-42 (Sep 2015) ISSN: 1672-7347 [Print] China
• PMID: 26408627 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anticoagulants
• Pipecolic Acids
• Sulfonamides
• Heparin
• Arginine
• argatroban

Topics

• Anticoagulants (adverse effects)
• Arginine (analogs & derivatives)
• Cardiac Surgical Procedures
• Heparin (adverse effects)
• Humans
• Incidence
• Infant
• Pipecolic Acids (therapeutic use)
• Platelet Count
• Prognosis
• Sulfonamides
• Thrombocytopenia (chemically induced)
• Thrombosis