Coming of Age: Breast Implant-Associated Anaplastic Large Cell Lymphoma After 18 Years of Investigation.

Abstract

Breast implant associated anaplastic large cell lymphoma (BIALCL) is a distinct clinical entity that can present in patients receiving either reconstructive or cosmetic breast implants. Presenting symptoms include onset of a delayed (>1 year after implantation) fluid collection, mass of the capsule, or lymphadenopathy. Treatment has progressed in recent years and most commonly includes implant removal and total resection of the tumor, including capsule, mass, and involved lymph nodes. Further research is warranted to determine potential malignant drivers, disease progression, and optimal treatment strategies in advanced disease.

• Authors: Mark W Clemens, Roberto N Miranda
• Journal: Clinics in plastic surgery (Clin Plast Surg) Vol. 42 Issue 4 Pg. 605-13 (Oct 2015) ISSN: 1558-0504 [Electronic] United States
• PMID: 26408447 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Review)
• Copyright: Copyright © 2015 Elsevier Inc. All rights reserved.

Topics

• Breast Implantation (adverse effects)
• Breast Implants (adverse effects)
• Breast Neoplasms (diagnosis, etiology, therapy)
• Device Removal
• Female
• Humans
• Lymphoma, Large-Cell, Anaplastic (diagnosis, etiology, therapy)