Transportal Radioembolization as Salvage Hepatocellular Carcinoma Therapy to Maintain Liver Transplant Candidacy.

Abstract

A 53-year-old woman with chronic hepatitis B and multifocal hepatocellular carcinoma was unable to receive transarterial radioembolization and had disease progression despite multiple chemoembolizations and systemic chemotherapy. Transportal radioembolization (TPRE) to maintain transplant candidacy was performed. Two lesions (1.7 cm, 1.4 cm) were treated with a single session of TPRE. Imaging performed at 4 months after TPRE demonstrated complete response in one lesion and stable disease in the other. This case illustrates TPRE as a salvage therapy for hepatocellular carcinoma in select patients.

• Authors: Beau B Toskich, David M Tabriz, Ivan Zendejas, Roniel Cabrera, Brian Geller
• Journal: Journal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 26 Issue 10 Pg. 1479-83 (Oct 2015) ISSN: 1535-7732 [Electronic] United States
• PMID: 26408214 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 SIR. Published by Elsevier Inc. All rights reserved.

Topics

• Carcinoma, Hepatocellular (diagnostic imaging, therapy)
• Chemoradiotherapy (methods)
• Combined Modality Therapy
• Eligibility Determination (methods)
• Embolization, Therapeutic (methods)
• Female
• Humans
• Liver Neoplasms (diagnostic imaging, therapy)
• Liver Transplantation (methods)
• Middle Aged
• Patient Selection
• Portal Vein (diagnostic imaging)
• Preoperative Care (methods)
• Radionuclide Imaging
• Salvage Therapy (methods)