Abstract | BACKGROUND: METHODS AND RESULTS: Using data from the Korea Working Group on Myocardial Infarction (February 2008-December 2011), this observational study included 2470 STEMI patients undergoing primary PCI who had not been diagnosed with diabetes mellitus either before or after admission (HbA1c at admission <6.5%). Patients were divided into two groups based on HbA1c at admission: prediabetic (5.7% ≤ HbA1c ≤ 6.4%, n=1475, 59.5%) and nondiabetic (HbA1c<5.7%, n=995, 40.5%). After analyzing the matched cohort, 1-year cumulative MACE incidence, defined as a composite of mortality, nonfatal myocardial infarction, repeated PCI, or coronary artery bypass graft, MACE was not found to differ significantly between the two groups (6.7 vs. 6.0%, P=0.616). Using multivariate logistic analysis, HbA1c level at admission was not significantly associated with the occurrence of MACE (odds ratio 0.925, 95% confidence interval 0.618-1.384, P=0.925). CONCLUSION: This study demonstrated that HbA1c level at admission was not significantly associated with cardiovascular outcomes in prediabetic Korean populations with STEMI undergoing primary PCI.
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Authors | Donghun Shin, Jinhee Ahn, Kwang Soo Cha, Jin Sup Park, Jun-Hyok Oh, Hye-Won Lee, Ju-Yong Hong, Bo-Won Kim, Taek Jong Hong, Korea Working Group on Myocardial Infarction Investigators |
Journal | Coronary artery disease
(Coron Artery Dis)
Vol. 27
Issue 1
Pg. 40-6
(Jan 2016)
ISSN: 1473-5830 [Electronic] England |
PMID | 26398151
(Publication Type: Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't)
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Chemical References |
- Blood Glucose
- Glycated Hemoglobin A
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Topics |
- Blood Glucose
(metabolism)
- Female
- Follow-Up Studies
- Glycated Hemoglobin
(metabolism)
- Humans
- Incidence
- Male
- Middle Aged
- Myocardial Infarction
(blood, epidemiology)
- Percutaneous Coronary Intervention
- Prediabetic State
(blood, complications, epidemiology)
- Prognosis
- Republic of Korea
(epidemiology)
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Survival Rate
(trends)
- Time Factors
- Treatment Outcome
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