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Near-infrared spectroscopy-intravascular ultrasound: scientific basis and clinical applications.

Abstract
Coronary angiography underestimates the magnitude of the atherosclerotic burden and cannot detect the presence of disease in the early phases. Recognition of these inherent limitations of angiography has been an impetus for the development of other coronary imaging techniques. The novel near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) catheters can detect and quantify the presence of lipid core in the atherosclerotic plaque and associate it with other features such as lumen size and plaque architecture. Lipid-rich plaques are known to pose a higher risk of distal embolization during interventions and plaque disruption. The aim of this manuscript is the review of the potential clinical and research applications of this technology as highlighted by recent studies.
AuthorsIsmail Dogu Kilic, Gianluca Caiazzo, Enrico Fabris, Roberta Serdoz, Sara Abou-Sherif, Sean Madden, Pedro R Moreno, James Goldstein, Carlo Di Mario
JournalEuropean heart journal. Cardiovascular Imaging (Eur Heart J Cardiovasc Imaging) Vol. 16 Issue 12 Pg. 1299-306 (Dec 2015) ISSN: 2047-2412 [Electronic] England
PMID26392514 (Publication Type: Journal Article, Review)
CopyrightPublished on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: [email protected].
Topics
  • Humans
  • Plaque, Atherosclerotic (diagnostic imaging)
  • Spectroscopy, Near-Infrared (methods)
  • Ultrasonography, Interventional (methods)

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