Refractive status and optical components of premature babies with or without retinopathy of prematurity at 3-4 years old.

Abstract

PURPOSE:

To investigate the refractive status and optical components of premature babies with or without retinopathy of prematurity (ROP) at 3-4 years old, and to explore the influence of prematurity and ROP on the refractive status and optical components.

METHODS:

Premature babies receiving fundus examination were recruited into ROP group and non-ROP group, with age-matched full-term babies as controls.

RESULTS:

The incidence of myopia was the highest in ROP (3/59, 5.08%). The incidence of astigmatism was significantly different between ROP (37.29%, 22/59) and controls (17.86%, 15/84). The corneal refractive power in ROP and non-ROP was more potent compared with controls (P<0.05); corneal curvature was steeper (P<0.05); lens thickness was thinner (P<0.05); ocular axial length was shorter P<0.05). The gestational age was negatively related to corneal astigmatism and astigmatism, positively associated with vitreous thickness and axial length. The birth-weight was negatively associated with corneal astigmatism, astigmatism and corneal refractive power, positively related to corneal radius of curvature, vitreous thickness and ocular axial length.

CONCLUSION:

Premature babies with or without ROP are susceptible to myopia and astigmatism. ROP, prematurity and low birth-weight synergistically influence the development of refractive status and optical components, of which the prematurity and low birth-weight are more important.

• Authors: Li-Juan Ouyang, Zheng-Qin Yin, Ning Ke, Xin-Ke Chen, Qin Liu, Jing Fang, Lin Chen, Xiu-Rong Chen, Hui Shi, Ling Tang, Lian-Hong Pi
• Journal: International journal of clinical and experimental medicine (Int J Clin Exp Med) Vol. 8 Issue 7 Pg. 11854-61 ( 2015) ISSN: 1940-5901 [Print] United States
• PMID: 26380027 (Publication Type: Journal Article)