Abstract | OBJECTIVE: METHODS: 158 diabetic patients with AMI undergone emergency PCI were randomly divided into three groups: Group A (53 cases) as the control group-dual anti-platelet agents ( aspirin + ticagrelor); Group B (52 cases)-dual anti-platelet agents + conventional dose of tirofiban [10 μg/kg by PCI and 0.15 μg/(kg·min) by continue venous pump for 24 h]; Group C (53 cases)-dual antiplatelet agents + half-dose tirofiban [10 μg/kg by PCI and 0.075 μg/(kg·min) by continue venous pump for 24 h]. RESULTS: Compared with group A, thrombolysis in myocardial infarction 3 (TIMI3) blood flow and TIMI myocardial perfusion grade 3 (TMPG3) myocardial perfusion of patients in group B and group C after PCI was significantly higher (P < 0.05), the average day of hospitalization was significantly shorter (P < 0.05), reinfarction during hospitalization, post- infarction angina, severe arrhythmia, the incidence of cardiac function above KillipIII level was significantly lower (P < 0.05). And the differences between group B and C was not statistically significant (P > 0.05). Severe bleeding and moderate incidence of bleeding in group B was significantly higher than that in group A and group C (P < 0.05). CONCLUSIONS:
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Authors | Yang Liu, Hengliang Liu, Zhenxuan Hao, Guoying Geng, Qi Chen, Wenjie Han, Kailong Jia, Yuxin Zhou |
Journal | International journal of clinical and experimental medicine
(Int J Clin Exp Med)
Vol. 8
Issue 7
Pg. 11360-9
( 2015)
ISSN: 1940-5901 [Print] United States |
PMID | 26379951
(Publication Type: Journal Article)
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