Multidetector Computed Tomography Features in Differentiating Exophytic Renal Angiomyolipoma from Retroperitoneal Liposarcoma: A Strobe-Compliant Observational Study.

Abstract

This study aims to evaluate the multidetector computed tomography (CT) imaging features in differentiating exophytic renal angiomyolipoma (AML) from retroperitoneal liposarcoma. We retrospectively enrolled 42 patients with confirmed exophytic renal AML (31 patients) or retroperitoneal liposarcoma (11 patients) during 8 years period to assess: renal parenchymal defect at site of tumor contact, supply from branches of renal artery, tumoral vessel extending through the renal parenchyma, dilated intratumoral vessels, hemorrhage, non-fat-containing intratumoral nodules with postcontrast enhancement, calcification, renal sinus enlargement, anterior displacement of kidneys, and other associated AML. Renal parenchymal defect, renal arterial blood supply, tumoral vessel through the renal parenchyma, dilated intratumoral vessels, intratumoral/perirenal hemorrhage, renal sinus enlargement, and associated AML were seen only or mainly in exophytic renal AML (all P value < 0.05); however, non-fat-attenuating enhancing intratumoral nodules, intratumoral calcification, and anterior displacement of the kidney were more common in liposarcoma (all P value < 0.05). AMLs reveal renal parenchymal defect at the site of tumor contact, supply from renal artery, tumoral vessel extending through the renal parenchyma, dilated intratumoral vessels, intratumoral and/or perirenal hemorrhage, renal sinus enlargement, and associated AML. Non-fat-attenuating enhancing intratumoral nodules, intratumoral calcifications, and anterior displacement of kidney were more commonly seen in liposarcoma.

• Authors: Qiushi Wang, Yu-Hsiang Juan, Yong Li, Jia-Jun Xie, Hui Liu, Hongfei Huang, Zaiyi Liu, Junhui Zheng, Ujwala S Saboo, Sachin S Saboo, Changhong Liang
• Journal: Medicine (Medicine (Baltimore)) Vol. 94 Issue 37 Pg. e1521 (Sep 2015) ISSN: 1536-5964 [Electronic] United States
• PMID: 26376398 (Publication Type: Journal Article, Observational Study)

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Angiomyolipoma (blood supply, complications, diagnosis)
• Calcinosis
• Diagnosis, Differential
• Female
• Hemorrhage (etiology)
• Humans
• Kidney (pathology)
• Kidney Neoplasms (blood supply, complications, diagnosis)
• Liposarcoma (diagnosis)
• Male
• Middle Aged
• Multidetector Computed Tomography
• Renal Artery (pathology)
• Retroperitoneal Neoplasms (diagnosis)
• Retrospective Studies
• Young Adult