A Novel Method for the Delivery of Antimetabolites During Glaucoma Surgery.

Abstract

Current techniques for the delivery of antimetabolites, such as mitomycin C, tend to be very variable among surgeons and risk uncontrolled contact with the conjunctivae, which may result in delayed wound healing, wound dehiscence, and wound leakage postoperatively. We describe a novel technique which appear to allow a more precise and reproducible delivery of antimetabolite to the target area with minimal contact with the conjunctival edge. The technique involves the injection of an antimetabolite-soaked wick into the subconjunctival space posterior to the scleral flap using an intraocular lens injector system.

• Authors: Kaleena B Michael, Donald M I Montgomery, James F T Li Yim
• Journal: Journal of glaucoma (J Glaucoma) Vol. 25 Issue 1 Pg. 132-3 (Jan 2016) ISSN: 1536-481X [Electronic] United States
• PMID: 26372151 (Publication Type: Journal Article)

Chemical References

• Antimetabolites
• Mitomycin

Topics

• Antimetabolites (administration & dosage)
• Drug Delivery Systems (methods)
• Glaucoma (surgery)
• Humans
• Intraocular Pressure
• Mitomycin (administration & dosage)
• Postoperative Complications
• Trabeculectomy (methods)