[Association of HLA with sarcoidosis].

Abstract

HLA typing for the A, B, C, and DR loci with 38 antigens was performed in 12 patients with sarcoidosis. It showed that an increase in frequencies of HLA-BW22, DR3 and DRw8 was significantly correlated with sarcoidosis (P less than 0.05). The results were similar to those in Japanese patients, and were quite different from those in the white as well as in the black and probably suggested that it varied with Asian population. No association between HLA and clinical symptoms, clinical signs, and laboratory tests was found in our patients, which was consistent with the views reported in recent literature.

• Authors: H D Wang
• Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases (Zhonghua Jie He He Hu Xi Za Zhi) Vol. 12 Issue 4 Pg. 200-3, 253 (Aug 1989) ISSN: 1001-0939 [Print] China
• PMID: 2636943 (Publication Type: Journal Article)

Chemical References

• HLA Antigens
• HLA-B Antigens
• HLA-B22 antigen
• HLA-DR3 Antigen

Topics

• Adult
• Asian People
• China
• Female
• HLA Antigens (analysis)
• HLA-B Antigens (analysis)
• HLA-DR3 Antigen (analysis)
• Humans
• Male
• Middle Aged
• Sarcoidosis (ethnology, genetics, immunology)