Television viewing and fatty liver in early midlife. The Cardiovascular Risk in Young Finns Study.

Abstract

INTRODUCTION:

Both sedentary behaviour and fatty liver are associated with increased risk of obesity and non-communicable diseases, but their relationship remains unknown. We investigated the relationship of television (TV) viewing time with serum gamma-glutamyltransferase (GGT) and Fatty Liver Index (FLI), and ultrasonographically assessed liver fat.

METHODS:

A total of 1,367 adults of the population-based Cardiovascular Risk in Young Finns study (748 women, 619 men, aged 34-49 years) had fasting serum GGT, triglycerides, weight, height, and waist circumference, and self-reported TV time data from 2001, 2007, and 2011. Changes in GGT and FLI, and liver ultrasound images in 2011 were studied in groups with constantly low (≤ 1 h/d), moderate (1-3 h/d), or high (≥ 3 h/d) daily TV time, and in groups with ≥ 1 hour increase/decrease in daily TV time between 2001 and 2011.

RESULTS:

Constantly high TV time was associated with higher GGT and FLI (P < 0.02 in both), and 2.3-fold (95% CI 1.2-4.5) increased risk of fatty liver regardless of age, sex, leisure-time and occupational physical activity, energy intake, diet composition, alcohol use, sleep duration, socioeconomic status, and smoking. Adjustment for BMI partly attenuated the associations.

CONCLUSIONS:

High TV viewing increases fatty liver risk. It may be one mechanism linking sedentary behaviour with increased cardiometabolic disease risks.

• Authors: Harri Helajärvi, Katja Pahkala, Olli J Heinonen, Markus Juonala, Mervi Oikonen, Tuija Tammelin, Nina Hutri-Kähönen, Mika Kähönen, Terho Lehtimäki, Vera Mikkilä, Jorma Viikari, Olli T Raitakari
• Journal: Annals of medicine (Ann Med) Vol. 47 Issue 6 Pg. 519-26 ( 2015) ISSN: 1365-2060 [Electronic] England
• PMID: 26362414 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Triglycerides
• gamma-Glutamyltransferase

Topics

• Adult
• Body Mass Index
• Body Weight
• Cardiovascular Diseases (blood, epidemiology)
• Female
• Finland (epidemiology)
• Humans
• Longitudinal Studies
• Male
• Middle Aged
• Non-alcoholic Fatty Liver Disease (blood, diagnostic imaging, epidemiology)
• Risk Factors
• Sedentary Behavior
• Television (statistics & numerical data)
• Triglycerides (blood)
• Ultrasonography
• Waist Circumference
• gamma-Glutamyltransferase (blood)