Thymoma-Associated Graft-Versus-Host-Like Disease With Skin Manifestations Improved by Complete Resection of Thymoma.

Abstract

A 69-year-old woman with refractory skin eruptions, which had first appeared 3 years previously, was examined, and an anterior mediastinal tumor was detected. The tumor was resected, and a diagnosis of type B2 thymoma, stage III disease (according to the World Health Organization classification), was made. Retrospectively, histologic findings of the skin before the operation were consistent with graft-versus-host disease. The final diagnosis of her skin lesions was thymoma-associated graft-versus-host-like disease. The skin lesions improved gradually during the 1-month period after resection with only a topical steroid, and further improvement was seen at 3 months.

• Authors: Makoto Motoishi, Keigo Okamoto, Ryosuke Kaku, Satoru Sawai, Jun Hanaoka
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 100 Issue 3 Pg. 1078-80 (Sep 2015) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 26354632 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Aged
• Exanthema (etiology)
• Female
• Graft vs Host Disease (etiology)
• Humans
• Remission Induction
• Thymoma (complications, surgery)
• Thymus Neoplasms (complications, surgery)