Hachimijiogan treatment is effective in the management of infertile women with hyperprolactinemia or bromocriptine-resistant hyperprolactinemia.

Abstract

Twenty-seven infertile women with hyperprolactinemia were treated with Hachimijiogan (5.0 to 10.0 g/day), Chinese herbal medicine. In 15 out of 18 patients, who were treated with Hachimijiogan, the serum prolactin levels dropped to 19.4 +/- 10.5 ng/ml during Hachimijiogan treatment, and the levels in 8 patients remained essentially unchanged during 6 months after the cessation of Hachimijiogan treatment. Three patients with 100 to 300 ng/ml did not drop to the level below 30 ng/ml. Four of 6 patients with amenorrhea ovulated. Eleven patients conceived and delivered normally. The hormonal profiles during or after pregnancy were normal. These results indicate that Hachimijiogan is a new safe treatment for hyperprolactinemic women.

• Authors: S Usuki, Y Usuki
• Journal: The American journal of Chinese medicine (Am J Chin Med) Vol. 17 Issue 3-4 Pg. 225-41 ( 1989) ISSN: 0192-415X [Print] Singapore
• PMID: 2633624 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Drugs, Chinese Herbal
• Bromocriptine
• Prolactin

Topics

• Adult
• Bromocriptine (therapeutic use)
• Drugs, Chinese Herbal (administration & dosage, pharmacology)
• Female
• Humans
• Hyperprolactinemia (complications, drug therapy)
• Infertility, Female (drug therapy, etiology)
• Ovulation (drug effects)
• Pregnancy
• Prolactin (blood)