Abstract | PURPOSE: MATERIALS AND METHODS: RESULTS: Comparing preoperative to postoperative medications at 12, 24 and 36-month followup, transplantation with concurrent ipsilateral nephrectomy had a greater decrease in quantity (-1.2 vs -0.5 medications, p=0.008; -1.1 vs -0.3, p=0.007 and -1.2 vs -0.4, p=0.03, respectively) and defined daily dose of antihypertensive drug (-3.3 vs -1.0, p=0.0008; -2.9 vs -1.0, p=0.006 and -2.7 vs -0.6, p=0.007, respectively) than transplantation alone at each point. Native nephrectomy continued to be a predictor of hypertensive requirements on multivariable analysis (p <0.0001). The mean decrease in number of medications in group 2b from after ipsilateral nephrectomy to 12 months after contralateral nephrectomy was -0.6 (p=0.0005) and the mean decrease in defined daily dose was -0.6 (p=0.009). CONCLUSIONS:
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Authors | Ashley M Shumate, Clinton D Bahler, William C Goggins, Asif A Sharfuddin, Chandru P Sundaram |
Journal | The Journal of urology
(J Urol)
Vol. 195
Issue 1
Pg. 141-6
(Jan 2016)
ISSN: 1527-3792 [Electronic] United States |
PMID | 26318985
(Publication Type: Journal Article)
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Copyright | Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Antihypertensive Agents
(administration & dosage)
- Drug Dosage Calculations
- Female
- Humans
- Hypertension
(complications, drug therapy)
- Kidney Transplantation
- Male
- Middle Aged
- Nephrectomy
- Polycystic Kidney, Autosomal Dominant
(complications, drug therapy)
- Retrospective Studies
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