Systemic antibiotics for treatment of the conjunctivitis-otitis media syndrome.

Abstract

In a private pediatric practice setting 114 episodes of conjunctivitis-otitis syndrome were treated with orally administered antibiotics. In 108 (95%) of these infections Haemophilus influenzae was isolated from the pretreatment cultures of the conjunctivae; 61 were susceptible and 47 (44%) were resistant to ampicillin by a disc diffusion technique. Six cultures grew Streptococcus pneumoniae, all ampicillin-susceptible. Symptoms of conjunctivitis disappeared in 2 to 3 days in all but one patient. Of the 48 follow-up conjunctival cultures 3 to 5 days after start of therapy, 46 grew no pathogens.

• Authors: F F Bodor
• Journal: The Pediatric infectious disease journal (Pediatr Infect Dis J) Vol. 8 Issue 5 Pg. 287-90 (May 1989) ISSN: 0891-3668 [Print] United States
• PMID: 2631693 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Cefaclor
• Ampicillin
• Cefixime
• Cefotaxime

Topics

• Administration, Oral
• Ampicillin (pharmacology, therapeutic use)
• Anti-Bacterial Agents (pharmacology, therapeutic use)
• Cefaclor (pharmacology, therapeutic use)
• Cefixime
• Cefotaxime (analogs & derivatives, pharmacology, therapeutic use)
• Child
• Child, Preschool
• Conjunctivitis, Bacterial (drug therapy, microbiology)
• Haemophilus Infections (drug therapy)
• Haemophilus influenzae (drug effects, isolation & purification)
• Humans
• Infant
• Microbial Sensitivity Tests
• Otitis Media (drug therapy, microbiology)
• Streptococcus pneumoniae (drug effects, isolation & purification)