Endodermal sinus tumor treated with high dose cisplatin.

Abstract

A woman with an endodermal sinus tumor of the ovary stage IV obtained a short but complete remission after treatment with vinblastine, bleomycin and standard dose cisplatin. A second complete remission for 42+ months was obtained with a regimen of vinblastine, bleomycin, etoposide, and high dose cisplatin. This result suggests a dose-response relationship for cisplatin in ovarian germ cell tumors.

• Authors: F E von Eyben, M Z Siddiqui, S Thunold
• Journal: Acta obstetricia et gynecologica Scandinavica (Acta Obstet Gynecol Scand) Vol. 68 Issue 7 Pg. 669-70 ( 1989) ISSN: 0001-6349 [Print] United States
• PMID: 2631536 (Publication Type: Journal Article)

Chemical References

• Cisplatin

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage)
• Cisplatin (administration & dosage)
• Dose-Response Relationship, Drug
• Female
• Humans
• Mesonephroma (drug therapy)
• Ovarian Neoplasms (drug therapy)