Palmar and plantar lichen planus: a case report and review of the literature.

Abstract

Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Immunohistochemical staining revealed positivity within the epidermis and/or lichenoid infiltrate with CD3, CD8, CD45, CD68, myeloid histiod antigen, BCL2, p27, p53, HLA-DPDQDR, metallothionein and tissue inhibitor of metalloproteinases 1. The diagnosis of PPLP was thus confirmed; this case illustrates that PPLP should be considered in the differential diagnosis of uncommon foot dermatoses with a significant junctional inflammatory component.

• Authors: Ana Maria Abreu Velez, Michael S Howard, Neville Pereyo
• Journal: Anais brasileiros de dermatologia (An Bras Dermatol) 2015 May-Jun Vol. 90 Issue 3 Suppl 1 Pg. 175-7 ISSN: 1806-4841 [Electronic] Spain
• PMID: 26312708 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adult
• Biopsy
• Diagnosis, Differential
• Epidermis (pathology)
• Foot Dermatoses (pathology)
• Hand Dermatoses (pathology)
• Humans
• Immunohistochemistry
• Lichen Planus (pathology)
• Male