Clinical response in Mexican patients with irritable bowel syndrome treated with a low diet low in fermentable carbohydrates (FODMAP).

Abstract

BACKGROUND:

The low FODMAP diet eliminates carbohydrates and fermentable alcohols because they are not absorbed by the intestine, but are fermented by the microbiota, causing bloating and flatulence.

AIMS:

To evaluate the clinical response to the low FODMAP diet in patients with the different clinical subtypes of irritable bowel syndrome (IBS).

MATERIALS AND METHODS:

Patients attended to at the Gastroenterology Department in 2014 that were diagnosed with IBS based on the Rome III criteria were included in the study. They were managed with a low FODMAP diet for 21 days and their response to the symptoms of abdominal pain, bloating, flatulence, and stool form pre and post-diet were evaluated through the visual analogue scale, Bristol scale, and patient overall satisfaction. The results were analyzed by means, 95% CI, and the Student's t test.

RESULTS:

Of the 31 patients included in the study, 87% were women and the mean age was 46.48 years. Distribution was: IBS-C 64.5%, IBS-D 22.6%, and IBS-M 12.9%. The score for pain was 6.0 (95% CI 5.04-6.96) and the post-diet score was 2.77 (95% CI 1.60-3.95) (P<.001). The score for bloating was 7.10 (95% CI 6.13-8.06) and the post-diet score was 4.19 (95% CI 2.95-5.44) (P<.001). The score for flatulence was 5.94 (95% CI 4.79-7.08) and the post-diet score was 3.06 (IC95% 1.99-4.14) (P<.001). The pre-diet Bristol Scale result was 3.68 (95% CI 3.14-4.22) and the post-diet result was 4.10 (95% CI 3.66-4.54) (P=.1). The satisfaction percentage was 70.9%.

CONCLUSIONS:

In this first study on a Mexican population with IBS, there was significant improvement of the main symptoms, including pain, bloating, and flatulence after treatment with a low FODMAP diet.

• Authors: N Pérez y López, E Torres-López, F Zamarripa-Dorsey
• Journal: Revista de gastroenterologia de Mexico (Rev Gastroenterol Mex) 2015 Jul-Sep Vol. 80 Issue 3 Pg. 180-5 ISSN: 0375-0906 [Print] Mexico
• PMID: 26300323 (Publication Type: Comparative Study, Journal Article)
• Copyright: Copyright © 2015 Asociación Mexicana de Gastroenterología. Published by Masson Doyma México S.A. All rights reserved.

Chemical References

• Dietary Carbohydrates

Topics

• Adult
• Aged
• Celiac Disease (diet therapy)
• Diet, Gluten-Free
• Dietary Carbohydrates (adverse effects)
• Female
• Humans
• Irritable Bowel Syndrome (complications, diagnosis, diet therapy)
• Longitudinal Studies
• Male
• Mexico
• Middle Aged
• Pain (etiology)
• Patient Satisfaction
• Prospective Studies
• Treatment Outcome
• Young Adult