[Linear immunoglobulin A bullous dermatosis: Two cases report].

Abstract

Linear immunoglobulin A bullous dermatosis is a rare entity with frequent spontaneous resolution. It usually presents in children with average age of 4.5 years. Its incidence is about 0.5-2.3 cases/million individuals/year. It is, after dermatitis herpetiformis, the most frequent paediatric blister disorder. It usually appears in bouts with acute development of vesicles in strings of pearls; affecting the perioral area and genitalia. Diagnosis is based on the clinical signs and symptoms and biopsy of the skin with subepidermal blister and a linear band of immunoglobulin A in the direct immunofluorescence. Often, diagnosis is made late because of the unawareness of this disease.

• Authors: Leticia González-Martín, Antonio González, María E Pérez-Martín
• Journal: Archivos argentinos de pediatria (Arch Argent Pediatr) Vol. 113 Issue 5 Pg. e279-82 (Oct 2015) ISSN: 1668-3501 [Electronic] Argentina
• Vernacular Title: Dermatosis ampollar por inmunoglobulina A lineal: Reporte de dos casos.
• PMID: 26294162 (Publication Type: Case Reports, Journal Article)

Topics

• Child, Preschool
• Female
• Humans
• Linear IgA Bullous Dermatosis (drug therapy, pathology)
• Male