Abstract | BACKGROUND: MATERIALS AND METHODS: We enrolled 75 patients in a retrospective, single-center study, including 25 patients who underwent orthotopic heart transplantation (heart transplant group) and 50 in the cardiac surgery group. They were in mean age of 49 ± 12 years and 51 ± 13 years in heart transplantation and cardiac surgery group, respectively. A gentamicin sponge was inserted intraoperatively between sternal borders before chest closure in all heart transplantation patients. RESULTS: There was 1 early death (4%) on postoperative day 7 owing to Clostridium difficile infection in the heart transplant group. There was 1 death (2%) in the cardiac surgery group owing to multiorgan failure secondary to perioperative heart ischemia. There was neither bacterial sternal wound infection nor sternal instability in the heart transplant group. None of the patients who had gentamicin sponge applied had wound healing problems. Two patients (4%) had a deep sternal wound infection in the cardiac surgery group, who had no sponge application; 1 (2%) was treated by surgical debridement and active drainage and 1 (2%) by vacuum therapy. There were 11 patients (44%) discharged on insulin therapy in the heart transplant group and 21 (21%) in the cardiac surgery group. Mean overall postoperative hospital stay was 35 ± 19 days in the heart transplant group and 10 ± 4 days in the cardiac surgery group. CONCLUSIONS:
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Authors | T Urbanowicz, E Straburzyńska-Migaj, P Buczkowski, S Grajek, M Jemielity |
Journal | Transplantation proceedings
(Transplant Proc)
2015 Jul-Aug
Vol. 47
Issue 6
Pg. 1954-7
ISSN: 1873-2623 [Electronic] United States |
PMID | 26293080
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 Elsevier Inc. All rights reserved. |
Chemical References |
- Anti-Bacterial Agents
- Gentamicins
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Topics |
- Adult
- Aged
- Animals
- Anti-Bacterial Agents
(administration & dosage)
- Female
- Gentamicins
(administration & dosage)
- Heart Transplantation
(adverse effects, methods)
- Humans
- Incidence
- Length of Stay
(statistics & numerical data)
- Male
- Middle Aged
- Retrospective Studies
- Surgical Sponges
- Surgical Wound Infection
(epidemiology, etiology, prevention & control)
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