Abstract | CONTEXT: EVIDENCE ACQUISITION:
Hyperuricemia is defined as a serum uric acid level > 7.0 mg/dL in males and > 6.0 mg/dL in females, while CKD is defined as kidney damage or a GFR < 60 mL/min/1.73 m(2) for 3 months or more, irrespective of the cause. Hyperuricemia is common in CKD and may occur because of decreased excretion, increased production, or a combination of both mechanisms. RESULTS: CONCLUSIONS: Although many evidence-based studies have suggested that uric acid itself may harm patients with CKD by increasing inflammation and CKD progression, the issue is still a matter of controversy. Special attention should be paid to specific contraindications to certain drugs and the possibility of infectious arthritis.
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Authors | Om Shankar Prasad Sah, Yu Xue Qing |
Journal | Nephro-urology monthly
(Nephrourol Mon)
Vol. 7
Issue 3
Pg. e27233
(May 2015)
ISSN: 2251-7006 [Print] Netherlands |
PMID | 26290849
(Publication Type: Journal Article, Review)
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