New medical strategies for the management of acute diverticulitis.

Abstract

Acute diverticulitis, defined as acute inflammation of a colonic diverticulum, is a common emergency presentation managed by both surgeons and physicians. There have been advances in the medical treatments offered to patients in recent years. Factors predisposing individuals to the development of acute diverticulitis include obesity, smoking, lack of physical activity and medication use, such as NSAIDs. Although widely used, there is limited evidence on the efficacy of individual antibiotic regimens and antibiotic treatment may not be required in all patients. Mesalazine seems to be the only effective treatment for the primary prevention of acute diverticulitis. Finally, evidence of effective measures for the prevention of recurrence is lacking. Furthermore, high-quality randomized controlled trials are required for medical treatments in patients with acute diverticulitis, if management is to be evidence based.

• Authors: Antonio Tursi
• Journal: Expert review of gastroenterology & hepatology (Expert Rev Gastroenterol Hepatol) Vol. 9 Issue 10 Pg. 1293-304 ( 2015) ISSN: 1747-4132 [Electronic] England
• PMID: 26289102 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents, Non-Steroidal
• Dietary Fiber
• Mesalamine

Topics

• Acute Disease
• Anti-Bacterial Agents (therapeutic use)
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Colonoscopy
• Dietary Fiber (administration & dosage)
• Diverticulitis, Colonic (diagnosis, epidemiology, etiology, therapy)
• Humans
• Mesalamine (therapeutic use)
• Primary Prevention (methods)
• Probiotics
• Secondary Prevention (methods)