[The use of buspirone in clinical practice].

Abstract

Buspirone, a nonbenzodiasepine anxiolytic, is a partial serotonin 5-HT1A-receptor agonist, D2-autoreceptor antagonist and low affinity 5-HT2-receptor agonist. This medication is used for treatment of generalized anxiety disorder though it may be prescribed in other anxiety states, primarily, panic disorder, sociophobia and depression. Buspirone seems to be potential in treatment of other neurological and mental disorders (tardive dyskinesia in Parkinson's disease, ataxia, behavioral disorders, cranial/brain injuries, dementia, attention-deficit hyperactivity disorder).

• Authors: O S Levin
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 115 Issue 4 Pg. 83-87 ( 2015) ISSN: 1997-7298 [Print] Russia (Federation)
• PMID: 26288293 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Anxiety Agents
• Serotonin 5-HT2 Receptor Agonists
• Buspirone

Topics

• Anti-Anxiety Agents (therapeutic use)
• Anxiety (drug therapy)
• Buspirone (therapeutic use)
• Depression (drug therapy)
• Dyskinesia, Drug-Induced (drug therapy)
• Humans
• Parkinson Disease (drug therapy)
• Phobic Disorders (drug therapy)
• Serotonin 5-HT2 Receptor Agonists (therapeutic use)