Secondary Hyperparathyroidism With "Superscan-Like" Hypermetabolic FDG PET/CT Pattern.

Abstract

A 26-year-old man with chronic terminal renal insufficiency under dialysis was referred in our institution for a checkup before kidney transplantation to ensure the absence of malignant neoplasm. The patient had a biological secondary hyperparathyroidism with highly elevated serum parathormon, and treatment with parathyroid surgery was planned before the kidney transplant. Whole-body FDG PET/CT showed no apparent malignant neoplasm, but increased metabolism of the 4 parathyroid gland and the other pitfalls of advanced secondary hyperparathyroidism on chronic renal insufficiency: pseudotumoral calcification in soft tissues, diffuse hypermetabolic bone dystrophy, and osteolytic lesion of pelvic and peripheral skeleton corresponding to brown tumors.

• Authors: Jean-Francois Grellier, David Lussato, Mathieu Queneau, Mohamed Guernou, Bernard Songy
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 40 Issue 11 Pg. 888-9 (Nov 2015) ISSN: 1536-0229 [Electronic] United States
• PMID: 26284774 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• Fluorodeoxyglucose F18

Topics

• Adult
• Bone and Bones (diagnostic imaging)
• Calcinosis (complications, diagnostic imaging)
• Fluorodeoxyglucose F18
• Humans
• Hyperparathyroidism, Secondary (complications, diagnostic imaging)
• Male
• Multimodal Imaging
• Parathyroid Glands (diagnostic imaging)
• Positron-Emission Tomography
• Radiopharmaceuticals
• Renal Insufficiency (complications, diagnostic imaging)
• Tomography, X-Ray Computed