HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Role of intraoperative indocyanine green video-angiography to identify small, posterior fossa arteriovenous malformations mimicking cavernous angiomas. Technical report and review of the literature on common features of these cerebral vascular malformations.

AbstractOBJECTIVE:
To illustrate the usefulness of intraoperative indocyanine green videoangiography (ICG-VA) to identify the nidus and feeders of a small cerebellar AVM resembling a cavernous hemangioma. To review the unique features regarding the overlay between these two vascular malformations and to highlight the importance to identify with ICG-VA, and treat accordingly, the arterial and venous vessels of the AVM.
METHODS:
A 36-year old man presented with bilateral cerebellar hemorrhage. MRI was equivocal in showing an underlying vascular malformation but angiography demonstrated a small, Spetzler-Martin grade I AVM. Surgical resection of the AVM with the aid of intraoperative ICG-VA was performed. After hematoma evacuation, pre-resection ICG-VA did not reveal tortuous arterial and venous vessels in keeping with a typical AVM but rather an unusual blackberry-like image resembling a cavernous hemangioma, with tiny surrounding vessels. Such intraoperative appearance, which could also be the consequence of a "leakage" of fluorescent dye from the nidal pathological vessels, with absent blood-brain barrier, into the surrounding parenchymal pathological capillary network, is important to be recognized as an unusual AVM appearance.
RESULTS:
Post-resection ICG-VA confirmed the AVM removal, as also shown by postoperative and 3-month follow-up DSAs.
CONCLUSIONS:
Despite technical limitations associated with ICG-VA in post-hemorrhage AVMs, this case together with the intraoperative video, demonstrates the useful role of ICG-VA in identifying small AVMs with peculiar features.
AuthorsGiuseppe M V Barbagallo, Francesco Certo, Rosario Caltabiano, Ignazio Chiaramonte, Vincenzo Albanese, Massimiliano Visocchi
JournalClinical neurology and neurosurgery (Clin Neurol Neurosurg) Vol. 138 Pg. 45-51 (Nov 2015) ISSN: 1872-6968 [Electronic] Netherlands
PMID26276727 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2015 Elsevier B.V. All rights reserved.
Chemical References
  • Coloring Agents
  • Indocyanine Green
Topics
  • Adult
  • Brain Neoplasms (diagnostic imaging)
  • Cerebral Angiography (methods)
  • Coloring Agents
  • Cranial Fossa, Posterior (abnormalities)
  • Craniotomy
  • Diagnosis, Differential
  • Hemangioma, Cavernous (diagnostic imaging)
  • Humans
  • Indocyanine Green
  • Intracranial Arteriovenous Malformations (diagnostic imaging, surgery)
  • Male
  • Video-Assisted Surgery (methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: