Abstract | BACKGROUND: The goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors. METHODS: A total of 24 cases with giant sacral neurogenic tumor were performed in a retrospective study between 2000 and 2012. Nineteen cases received surgical resection, and five cases received non-surgical treatment. In surgical group, patients with type III sacral tumor had received a combined anterior-posterior approach and patients with type IV were treated with simple anterior approach. In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels. Besides, CT scanning or magnetic resonance imaging was used to assess the size and development of tumors. RESULTS: Two of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up. Patients in non-surgical group were followed up for 2-8 years. CONCLUSIONS: Our study suggested that CT-guided 125I seed implantation or GSP embolization treatment is very useful to slow down the development of giant benign sacral neurogenic tumors.
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Authors | Xiaojun Ma, Sun Wei, Chunxi Yang, Yingqi Hua, Jiakang Shen, Zhengdong Cai |
Journal | World journal of surgical oncology
(World J Surg Oncol)
Vol. 13
Pg. 247
(Aug 15 2015)
ISSN: 1477-7819 [Electronic] England |
PMID | 26271355
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Brachytherapy
- Embolization, Therapeutic
- Female
- Follow-Up Studies
- Gelatin Sponge, Absorbable
- Humans
- Iodine Radioisotopes
(therapeutic use)
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Neoplasm Staging
- Neurosurgical Procedures
(methods)
- Prognosis
- Retrospective Studies
- Sacrum
(radiation effects, surgery)
- Spinal Neoplasms
(pathology, radiotherapy, surgery)
- Tomography, X-Ray Computed
- Young Adult
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