Abstract | BACKGROUND:
Synovial sarcoma account for approximately 10 % of all soft-tissue tumors and occur most frequently in young adults. A specific translocation in this sarcoma induces fusion of the SYT gene on chromosome 18 to the SSX genes on chromosome X, leading to proliferation of the tumor cells. The need for non-invasive biomarkers indicating recurrence and activity of this disease has sparked research into short non-coding RNA known as microRNA ( miRNA). METHODS: RESULTS: CONCLUSION:
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Authors | Alba Fricke, Prisca V Ullrich, Jürgen Heinz, Dietmar Pfeifer, Jutta Scholber, Georg W Herget, Oliver Hauschild, Peter Bronsert, G Björn Stark, Holger Bannasch, Steffen U Eisenhardt, David Braig |
Journal | Molecular cancer
(Mol Cancer)
Vol. 14
Pg. 151
(Aug 07 2015)
ISSN: 1476-4598 [Electronic] England |
PMID | 26250552
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers, Tumor
- MicroRNAs
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Topics |
- Biomarkers, Tumor
- Case-Control Studies
- Cluster Analysis
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- MicroRNAs
(blood, genetics)
- Sarcoma, Synovial
(blood, genetics)
- Transcriptome
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