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[Modern Views on Children's Interstitial Lung Disease].

Abstract
Interstitial lung diseases (ILD, diffuse lung diseases) are a heterogeneous group of diseases in which a pathological process primarily involved alveoli and perialveolar interstitium, resulting in impaired gas exchange, restrictive changes of lung ventilation function and diffuse interstitial changes detectable by X-ray. Children's interstitial lung diseases is an topical problem ofpediatricpulmonoogy. The article presents current information about classification, epidemiology, clinical presentation, diagnostics, treatment and prognosis of these rare diseases. The article describes the differences in the structure, pathogenesis, detection of various histological changes in children's ILD compared with adult patients with ILD. Authors cite an instance of registers pediatric patients with ILD. The clinical semiotics of ILD, the possible results of objective research, the frequency of symptoms, the features of medical history, the changes detected on chest X-rays, CT semiotics described in detail. Particular attention was paid to interstitial lung diseases, occurring mainly in newborns and children during the first two years of life, such as congenital deficiencies of surfactant proteins, neuroendocrine cell hyperplasia of infancy, pulmonary interstitial glycogenosis. The diagnostic program for children's ILD, therapy options are presented in this article.
AuthorsE V Boĭtsova, M A Beliashova, D Iu Ovsiannikov
JournalVestnik Rossiiskoi akademii meditsinskikh nauk (Vestn Ross Akad Med Nauk) Issue 2 Pg. 227-36 ( 2015) ISSN: 0869-6047 [Print] Russia (Federation)
PMID26234096 (Publication Type: English Abstract, Journal Article, Review)
Topics
  • Child
  • Diagnostic Imaging (methods)
  • Disease Management
  • Humans
  • Lung (physiopathology)
  • Lung Diseases, Interstitial (diagnosis, physiopathology, therapy)
  • Prognosis

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