HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

[The sex steroid content of the blood serum in women suffering from postmenopausal osteoporosis].

Abstract
The levels of estradiol, estrone, androstendione, and testosterone were investigated in 25 women aged 56-69 with postmenopausal osteoporosis and in healthy women using radioimmunoassays. Relatively high levels of estradiol, estrone and androstendione were revealed in the study group as compared to the control group. The results obtained showed no association between the development of postmenopausal osteoporosis and deficiency of estrogens because in the healthy controls a decrease in the level of sex hormones was more noticeable. Taking into account the mechanism of the effect of estrogens on osseous tissue and its receptors, calcitonin secretion and, possibly, vitamin D3 synthesis, one can regard a relative elevation of the level of estrogens in postmenopausal osteoporosis as a compensatory protective phenomenon.
AuthorsI I Dorokhova, N A Zarubina, S S Rodionova
JournalProblemy eĚŠndokrinologii (Probl Endokrinol (Mosk)) 1989 Nov-Dec Vol. 35 Issue 6 Pg. 35-8 ISSN: 0375-9660 [Print] USSR
Vernacular TitleSoderzhanie polovykh steroidov v syvorotke krovi zhenshchin, stradaiushchikh postmenopauzal'nym osteoporozom.
PMID2622883 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Androgens
  • Estrogens
  • Estrone
  • Testosterone
  • Androstenedione
  • Estradiol
Topics
  • Aged
  • Androgens (blood)
  • Androstenedione (blood)
  • Chronic Disease
  • Estradiol (blood)
  • Estrogens (blood)
  • Estrone (blood)
  • Female
  • Humans
  • Middle Aged
  • Osteoporosis, Postmenopausal (blood)
  • Radioimmunoassay
  • Spinal Diseases (blood)
  • Testosterone (blood)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: